4-Methylbenzimidamide

4-Methylbenzimidamide

SCHEMBL524027

Cc1ccc(C(=N)N)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
PLAU P00749 2/20 0.59
MASP2 O00187 1/20 0.59
THPO P40225 1/20 0.59
PRSS1 P07477 6/20 0.56
PRSS3 P35030 6/20 0.56
PRSS2 P07478 5/20 0.56
F2 P00734 3/20 0.56
C1S P09871 2/20 0.56
APEX1 P27695 1/20 0.56
NQO2 P16083 2/20 0.56
F10 P00742 2/20 0.55
F12 P00748 1/20 0.55
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PKM P14618 1/20 0.55
ST14 Q9Y5Y6 1/20 0.54
PRMT5 O14744 1/20 0.54
PRMT1 Q99873 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzimidamide SCHEMBL28504756 0.97 PRSS1 (0.61) LMNAPLAUMASP2THPOPRSS1
4-Methylbenzimidamide SCHEMBL1019464 0.97 PRSS1 (0.61) LMNAPLAUMASP2THPOPRSS1
4-Methylbenzimidamide SCHEMBL1436204 0.95 LMNA (0.54) LMNAPLAUMASP2THPOPRSS1
4-Methylbenzimidamide SCHEMBL28496422 0.95 PRSS1 (0.58) LMNAPLAUMASP2THPOPRSS1
SCHEMBL12461484 0.93 WDR5 (0.64) LMNAPLAUMASP2THPOPRSS1
4-Methylbenzimidamide SCHEMBL28399173 0.89 BLM (0.74) LMNAPLAUMASP2THPOPRSS1
SCHEMBL20364177 0.87 ST14 (0.79) PLAUPRSS1PRSS3PRSS2F2
4-Methylbenzimidamide SCHEMBL1050355 0.87 NQO2 (0.51) LMNAPLAUMASP2THPOPRSS1
SCHEMBL537030 0.85 LMNA (0.77) LMNAPLAUMASP2THPOPRSS1
4-Methylbenzimidamide SCHEMBL15844882 0.85 NQO2 (0.50) LMNAPLAUMASP2THPOPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240228-A Hypoxia-responsive carrier protein hydrogen bond organic framework, preparation method and application 天津市肿瘤医院(天津医科大学肿瘤医院) 2024-06-25 CN claimed
CN-114380826-B Perylene porous organic salt material with stable light and heat properties, and preparation method and application thereof 吉林大学 2024-02-23 CN claimed
CN-113383039-B Moisture curable polyolefin formulation 陶氏环球技术有限责任公司 2023-09-26 CN claimed
CN-114845471-B Oil removing and hole finishing method for PTH (plated through hole) process of printed circuit board, alkaline oil removing and hole finishing agent and preparation method thereof 深圳市板明科技股份有限公司 2022-09-27 CN claimed
CN-114845471-A Oil removing and hole finishing method for PTH (plated through hole) process of printed circuit board, alkaline oil removing and hole finishing agent and preparation method thereof 深圳市板明科技股份有限公司 2022-08-02 CN claimed
CN-114380826-A Perylene porous organic salt material with stable photo-thermal property and preparation method and application thereof 吉林大学 2022-04-22 CN claimed
US-20220098432-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-03-31 US claimed
EP-3924419-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION Dow Global Technologies LLC (US) 2021-12-22 EP claimed
CN-113383039-A Moisture curable polyolefin formulations 陶氏环球技术有限责任公司 2021-09-10 CN claimed
WO-2020164004-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-08-20 WO claimed
US-6287794-B1 Factor Vlla inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-09-11 US claimed
US-5705487-A PEPTIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1998-01-06 US claimed
EP-0627925-A4 TRYPSIN INHIBITORS. CORVAS INT INC (US) 1997-07-30 EP claimed
US-5534498-A TREATMENT OF PANCREATITIS CORVAS INTERNATIONAL, INC. (US) 1996-07-09 US claimed
EP-0627925-A1 TRYPSIN INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1994-12-14 EP claimed
WO-1993014779-A1 TRYPSIN INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1993-08-05 WO claimed
US-5043447-A Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives SYNTEX PHARMACEUTICALS, LTD. (GB) 1991-08-27 US claimed
EP-0103126-B1 PROCESS FOR PREPARING 4-AMINO-5-DIALKOXYMETHYLPYRIMIDINE DERIVATIVES UBE INDUSTRIES, LTD. (JP) 1987-03-04 EP claimed
US-4492792-A Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives UBE INDUSTRIES, LTD. (JP) 1985-01-08 US claimed
EP-0103126-A1 Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives UBE INDUSTRIES, LTD. (JP) 1984-03-21 EP claimed