Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL10638262 | 0.86 | ALOX15 (0.59) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL65889 | 0.86 | ALOX15 (0.59) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL15641523 | 0.85 | TTR (0.43) | MMP2ALDH1A1TTRMAPTGAA | |
| SCHEMBL28069384 | 0.85 | MMP2 (0.55) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL812165 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL3781304 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 | |
| Phosphine SCHEMBL3820807 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL20471934 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 | |
| Phosphine SCHEMBL3135561 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 | |
| SCHEMBL143947 | 0.84 | ALOX15 (0.57) | MMP2ALOX15CASP7G6PDCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109889-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | US | disclosed |
| US-11787802-B2 | Dihydrobenzimidazolones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220289738-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| US-11254672-B2 | Dihydrobenzimidazolones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| CN-215123347-U | Automatic metal wire code manufacturing device | 浙江海洋大学 | 2021-12-14 | — | — | CN | disclosed |
| US-20200207764-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2020-07-02 | — | — | US | disclosed |
| US-8697739-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2014-04-15 | — | — | US | disclosed |
| WO-2012159116-A2 | FLUORESCENT PROBES FOR MONITORING VOLTAGE BY PHOTO-INDUCED ELECTRON TRANSFER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-22 | — | — | WO | disclosed |
| US-20120028969-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | US | disclosed |
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2011-12-01 | — | — | US | disclosed |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
| US-20100124713-A1 | TONERS INCLUDING CARBON NANOTUBES DISPERSED IN A POLYMER MATRIX | XEROX CORPORATION (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100122642-A1 | INKS INCLUDING CARBON NANOTUBES DISPERSED IN A POLYMER MATRIX | XEROX CORPORATION (US) | 2010-05-20 | — | — | US | disclosed |
| EP-2187266-A1 | Toners including carbon nanotubes dispersed in a polymer matrix | Xerox Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207764-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | CRBN, CUL4A, ADRM1 | MMP2 3896/4885ALOX15 4668/4885CASP7 3493/4885 |
| US-20120028969-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | ACACA, ACACB, COASY | MMP2 1751/4885ALOX15 1133/4885CASP7 4321/4885 |
| US-20240109889-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | CRBN, CUL4A, ADRM1 | MMP2 3896/4885ALOX15 4668/4885CASP7 3493/4885 |
| US-20220289738-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | CRBN, CUL4A, ADRM1 | MMP2 3896/4885ALOX15 4668/4885CASP7 3493/4885 |
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | MMP2 2257/4885ALOX15 10/4885CASP7 1657/4885 |
| US-11787802-B2 | Dihydrobenzimidazolones for medical treatment | CRBN, CUL4A, ADRM1 | MMP2 3896/4885ALOX15 4668/4885CASP7 3493/4885 |
| US-11254672-B2 | Dihydrobenzimidazolones for medical treatment | CRBN, CUL4A, ADRM1 | MMP2 3896/4885ALOX15 4668/4885CASP7 3493/4885 |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | MMP2 1220/4885ALOX15 18/4885CASP7 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.