Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778320 | 0.82 | ADH1A (0.45) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL11529363 | 0.77 | ALDH1A1 (0.36) | ADH1AADH1CMEN1KMT2AALDH1A1 | |
| SCHEMBL11531320 | 0.74 | ADH1A (0.42) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL5459487 | 0.73 | SLC6A4 (0.40) | ADH1AADH1CL3MBTL1NPSR1S1PR1 | |
| SCHEMBL5449617 | 0.73 | SLC6A4 (0.40) | ADH1AADH1CL3MBTL1NPSR1S1PR1 | |
| SCHEMBL6259261 | 0.73 | ADH1A (0.38) | ADH1AADH1CL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL11528739 | 0.72 | L3MBTL1 (0.45) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL11519507 | 0.70 | ADH1A (0.35) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL8944256 | 0.70 | ALDH1A1 (0.36) | ADH1AADH1CMEN1KMT2AALDH1A1 | |
| SCHEMBL3891941 | 0.69 | OPRM1 (0.43) | ADH1AADH1CL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |