Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.40 |
| ▸ | MIF | P14174 | 3/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | DDT | P30046 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247693 | 0.91 | LOX (0.40) | LOXLOXL2MIFPRSS12APP | |
| SCHEMBL5244109 | 0.87 | MIF (0.47) | MIFSMN1; SMN2 | |
| SCHEMBL5246041 | 0.86 | MIF (0.45) | MIFGLSDDTEPHX2DRD2 | |
| SCHEMBL5250280 | 0.86 | NPSR1 (0.36) | MIFPRSS12GLSDDTEPHX2 | |
| SCHEMBL5246315 | 0.84 | HPGD (0.39) | EPHX2 | |
| SCHEMBL5244350 | 0.84 | ROCK2 (0.38) | MIFDDTPSEN1PSEN2APH1B | |
| SCHEMBL5248109 | 0.83 | EGLN1 (0.38) | LOXL2MIFGLSDDTEPHX2 | |
| Trifluoroacetic Acid SCHEMBL5247737 | 0.83 | GLS (0.42) | GLSSMN1; SMN2 | |
| SCHEMBL3104911 | 0.83 | S1PR1 (0.41) | LOXL2DRD2DRD3 | |
| SCHEMBL5246077 | 0.83 | MMP13 (0.37) | MIFDDTEPHX2SMN1; SMN2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |