Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 3/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | DDT | P30046 | 2/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246551 | 0.93 | RIPK1 (0.34) | GLSLGALS3NOTUM | |
| SCHEMBL5248284 | 0.91 | NPSR1 (0.37) | NPSR1SCDGLSMIFNOTUM | |
| SCHEMBL5245554 | 0.90 | GABRA5 (0.36) | SCDGLSLGALS3EPHX2PRSS12 | |
| SCHEMBL5244109 | 0.87 | MIF (0.47) | NPSR1MIFRXFP1 | |
| SCHEMBL5244601 | 0.86 | LOX (0.40) | GLSEPHX2MIFDDTPRSS12 | |
| SCHEMBL5245570 | 0.86 | LMNA (0.42) | LGALS3EPHX2NOTUMDDT | |
| SCHEMBL5246799 | 0.85 | PSEN1 (0.41) | NPSR1GLSMIFDDT | |
| SCHEMBL5248109 | 0.85 | EGLN1 (0.38) | GLSEPHX2MIFDDT | |
| SCHEMBL5246041 | 0.85 | MIF (0.45) | GLSEPHX2MIFDDT | |
| SCHEMBL5250510 | 0.85 | DDT (0.41) | EPHX2MIFDDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |