Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | MIF | P14174 | 3/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244601 | 0.91 | LOX (0.40) | LOXLOXL2MIFPRSS12APP | |
| SCHEMBL5247626 | 0.86 | MIF (0.48) | MIFSMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL5246767 | 0.86 | MIF (0.47) | BRD4MIFSMN1; SMN2 | |
| SCHEMBL5248284 | 0.86 | NPSR1 (0.37) | BRD4MIFPRSS12APP | |
| SCHEMBL5250093 | 0.84 | ROCK2 (0.41) | BRD4MAPTRAB9A | |
| SCHEMBL5248700 | 0.83 | ROCK2 (0.41) | BRD4MIFKLKB1MAPT | |
| SCHEMBL5244706 | 0.83 | ROCK2 (0.40) | BRD4MIF | |
| SCHEMBL5244462 | 0.82 | MAPT (0.40) | BRD4MIFSMN1; SMN2MAPT | |
| SCHEMBL5248058 | 0.82 | PRSS12 (0.36) | BRD4MIFPRSS12KLKB1MAPT | |
| SCHEMBL5246579 | 0.82 | WDR5 (0.38) | BRD4MIFAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |