Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250280 | 0.93 | NPSR1 (0.36) | LGALS3NOTUMGLS | |
| SCHEMBL5244299 | 0.91 | BRD4 (0.35) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244507 | 0.88 | BRD4 (0.40) | DRD2DRD3 | |
| SCHEMBL3104911 | 0.87 | S1PR1 (0.41) | S1PR1LGALS3NOTUMDRD2DRD3 | |
| SCHEMBL3102931 | 0.85 | TP53 (0.39) | DRD2DRD3 | |
| SCHEMBL5248284 | 0.84 | NPSR1 (0.37) | NOTUMGLSHDAC8 | |
| SCHEMBL5248217 | 0.83 | NAMPT (0.38) | GLSKCNH2SCN9A | |
| SCHEMBL5245554 | 0.83 | GABRA5 (0.36) | S1PR1LGALS3GLSHDAC8 | |
| SCHEMBL5245310 | 0.83 | DRD2 (0.38) | RIPK1DRD2DRD3 | |
| SCHEMBL3109192 | 0.83 | ACKR3 (0.40) | DRD2DRD3GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |