Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | SCD | O00767 | 3/20 | 0.34 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244299 | 0.92 | BRD4 (0.35) | BRD4 | |
| SCHEMBL5250280 | 0.91 | NPSR1 (0.36) | NPSR1SCDPRSS12MIFGLS | |
| SCHEMBL5248058 | 0.90 | PRSS12 (0.36) | BRD4SCDPRSS12MIFHDAC8 | |
| SCHEMBL5247626 | 0.87 | MIF (0.48) | NPSR1MIF | |
| SCHEMBL5247693 | 0.86 | LOX (0.40) | BRD4PRSS12MIFAPP | |
| SCHEMBL5247657 | 0.85 | LMNA (0.46) | BRD4MIFNOTUMHDAC8 | |
| SCHEMBL5246767 | 0.85 | MIF (0.47) | BRD4MIFGLS | |
| SCHEMBL5244706 | 0.85 | ROCK2 (0.40) | BRD4MIF | |
| SCHEMBL5246245 | 0.85 | ROCK2 (0.41) | BRD4MIF | |
| SCHEMBL5244462 | 0.84 | MAPT (0.40) | BRD4MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |