Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248058 | 0.92 | PRSS12 (0.36) | PRSS12EPHX2TP53MAPTHDAC8 | |
| SCHEMBL5250280 | 0.90 | NPSR1 (0.36) | PRSS12EPHX2GLSSCDLGALS3 | |
| SCHEMBL5250510 | 0.84 | DDT (0.41) | EPHX2 | |
| SCHEMBL5244109 | 0.84 | MIF (0.47) | MAPT | |
| SCHEMBL5246551 | 0.83 | RIPK1 (0.34) | HDAC8GLSS1PR1LGALS3 | |
| SCHEMBL5244601 | 0.82 | LOX (0.40) | PRSS12EPHX2GLS | |
| SCHEMBL5246800 | 0.82 | EPHX2 (0.38) | EPHX2SCD | |
| SCHEMBL5245570 | 0.82 | LMNA (0.42) | EPHX2HDAC8LGALS3 | |
| SCHEMBL5244350 | 0.82 | ROCK2 (0.38) | GABRA5 | |
| SCHEMBL5246041 | 0.82 | MIF (0.45) | EPHX2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |