SCHEMBL525216

SCHEMBL525216

Cc1cc(N)cc(C)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.47
TSHR P16473 5/20 0.47
PDE10A Q9Y233 1/20 0.40
CASP1 P29466 2/20 0.38
CYP3A4 P08684 6/20 0.36
TDP1 Q9NUW8 3/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 1/20 0.36
SOS1 Q07889 1/20 0.35
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
THRB P10828 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
ALOX15 P16050 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CD44 P16070 1/20 0.32
ACHE P22303 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21175202 0.97 ALDH1A1 (0.45) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL15573628 0.86 ALDH1A1 (0.41) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL524410 0.83 GAA (0.40) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL38651837 0.82 GAA (0.46) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL22644377 0.82 CYP3A4 (0.48) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL13928793 0.82 ALDH1A1 (0.38) ALDH1A1TSHRPDE10ACASP1
Hydrochloric Acid SCHEMBL524876 0.82 GAA (0.43) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL25112322 0.78 NOS3 (0.39) ALDH1A1TSHRPDE10AMAPTKMT2A
SCHEMBL16236972 0.78 TSHR (0.43) ALDH1A1TSHRPDE10AMAPK1MAPT
SCHEMBL16236862 0.77 KDM4E (0.40) ALDH1A1TSHRMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US claimed
CN-118388315-A Method for synthesizing 1, 5-dibromo-2, 4-bis (bromomethyl) -3-fluorobenzene and application thereof 常州贝迪佳尔生物科技有限公司 2024-07-26 CN claimed
EP-0488756-B1 Oxidizable color producing reagent WAKO PURE CHEM IND LTD (JP) 1997-02-26 EP claimed
CN-122079814-A Synthesis method of 4-fluoro-3, 5-dimethylbenzene hydrazine hydrochloride 2026-05-26 CN disclosed
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-16 US disclosed
US-20260055105-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
CN-120757464-A Preparation method of 4-fluoro-3, 5-dimethylbenzene hydrazine hydrochloride 内蒙古幸源新材料科技有限公司 2025-10-10 CN disclosed
US-12410168-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12391663-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS AG (CH) 2025-08-19 US disclosed
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US disclosed
WO-2025137307-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. (US) 2025-06-26 WO disclosed
US-20120028923-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY RIGEL PHARMACEUTICALS, INC. 2012-02-02 US disclosed
US-20120028923-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY RIGEL PHARMACEUTICALS, INC. 2012-02-02 US disclosed
WO-2008094592-A1 HYDROXAMIC ACID DERIVATIVES OF ANILINE USEFUL AS THERAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING PANTHERA BIOPHARNA, LLC (US) 2008-08-07 WO disclosed
EP-0488756-B1 Oxidizable color producing reagent WAKO PURE CHEM IND LTD (JP) 1997-02-26 EP disclosed
US-5279714-A Reductive fluorination of nitrobenzene IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-18 US disclosed
US-5238818-A Derivative of p-fluoroaniline with 4-aminoantipyrine WAKO PURE CHEMICALS CO., LTD. (JP) 1993-08-24 US disclosed
EP-0508578-A2 Preparation of Fluoroanilines by Electrochemical Means ZENECA LIMITED (GB) 1992-10-14 EP disclosed
EP-0488756-A1 Oxidizable color producing reagent WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-06-03 EP disclosed
US-4145364-A PREPARATION OF FLUORINATED ANILINES MERCK & CO., INC. (US) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410168-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR ALDH1A1 2311/4885TSHR 301/4885PDE10A 1330/4885
US-12391663-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 ALDH1A1 1142/4885TSHR 1114/4885PDE10A 2695/4885
US-20120028923-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY JAK3, JAK2, JAK1 ALDH1A1 3686/4885TSHR 4061/4885PDE10A 1334/4885
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR ALDH1A1 2886/4885TSHR 61/4885PDE10A 713/4885
US-20260055105-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GIPR, GPR119 ALDH1A1 2878/4885TSHR 375/4885PDE10A 988/4885
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture NOS1, NOS3, NOS2 ALDH1A1 754/4885TSHR 4597/4885PDE10A 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.