Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.89 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL3996061 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL905185 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL3996055 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL30165925 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL21641709 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL28333179 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL27515168 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL30216954 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL27423286 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL1330659 | 0.94 | CYP2A6 (1.00) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3477 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800689-B | Prestressed duct grouting material for negative temperature and preparation method thereof | CCCC WUHAN HARBOUR ENGINEERING DESIGN AND RESEARCH Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122079587-A | Early-strength high-stability grouting repair material for road and preparation thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080889-A | Coal rock drill cuttings gelling agent and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079571-A | Process for preparing high-strength high-permeability-resistance cement-based material based on modified regenerated micro powder | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079567-A | Self-repairing type single-component polymer waterproof mortar and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-116789416-B | High-strength high-ductility concrete and preparation method and application thereof | Shandong Luqiao building materials Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-118005355-B | Compression-resistant dry-mixed mortar and preparation method thereof | Gaobeidian Lvrong Decoration Materials Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122079591-A | Multifunctional composite material and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122071389-A | Electromagnetic wave shielding concrete capable of being pumped for more than 20m and preparation method thereof | 中国建筑材料科学研究总院有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-122071387-A | High-performance electromagnetic shielding concrete and electromagnetic shielding room construction method | 中国建筑材料科学研究总院有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-111635195-B | Seawater sea sand concrete and preparation method thereof | 朱峣霖 | 2022-01-21 | — | — | CN | claimed |
| CN-113955995-A | Sudden thermal cracking resistant quartz stone patterned artificial stone plate and preparation method thereof | 华润水泥技术研发有限公司 | 2022-01-21 | — | — | CN | claimed |
| US-20150118395-A1 | Vapor Deposition of Metal Oxides, Silicates and Phosphates, and Silicon Dioxide | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2015-04-30 | — | — | US | claimed |
| CN-1976696-B | Pharmaceutical composition for prevention or treatment of lipid metabolism disorder | KISSEI PHARMACEUTICAL | 2010-10-06 | — | — | CN | claimed |
| CN-1976696-A | Pharmaceutical composition for prevention or treatment of lipid metabolism disorder | KISSEI PHARMACEUTICAL (JP) | 2007-06-06 | — | — | CN | claimed |
| US-6969539-B2 | Vapor deposition of metal oxides, silicates and phosphates, and silicon dioxide | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-11-29 | — | — | US | claimed |
| JP-2004527651-A | — | — | 2004-09-09 | — | — | JP | claimed |
| US-20040043149-A1 | Vapor deposition of metal oxides, silicates and phosphates, and silicon dioxide | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-03-04 | — | — | US | claimed |
| EP-1327010-A2 | VAPOR DEPOSITION OF OXIDES, SILICATES AND PHOSPHATES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2003-07-16 | — | — | EP | claimed |
| WO-2002027063-A2 | VAPOR DEPOSITION OF OXIDES, SILICATES AND PHOSPHATES | PRESIDENT AND FELLOWS OF HARWARD COLLEGE (US) | 2002-04-04 | — | — | WO | claimed |