Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.89 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL3996061 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL3996055 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL30165925 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL21641709 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL525284 | 1.00 | CYP2A6 (0.89) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL28333179 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL27515168 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL30216954 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL27423286 | 0.95 | CYP2A6 (0.80) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL1330659 | 0.94 | CYP2A6 (1.00) | CYP2A6ALOX12ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175951-B | Resin composition, cured product, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board | 三菱瓦斯化学株式会社 | 2024-07-12 | — | — | CN | claimed |
| CN-115505099-B | Epoxy resin containing carbazole structure, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115505100-B | Epoxy resin based on spirosilafluorene as framework, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118251457-A | Thermosetting resin composition, prepreg and printed wiring board | 三菱瓦斯化学株式会社 | 2024-06-25 | — | — | CN | claimed |
| CN-117836369-A | Curable composition, prepreg, metal foil-clad laminate, and printed wiring board | 三菱瓦斯化学株式会社 | 2024-04-05 | — | — | CN | claimed |
| CN-117795003-A | Curable composition, prepreg, metal foil-clad laminate, and printed wiring board | 三菱瓦斯化学株式会社 | 2024-03-29 | — | — | CN | claimed |
| CN-117397372-A | Resin composition, prepreg, resin sheet, laminate, metal foil-clad laminate, and printed wiring board | 三菱瓦斯化学株式会社 | 2024-01-12 | — | — | CN | claimed |
| CN-116987386-A | Resin composition and use thereof | 苏州生益科技有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-114539709-B | Resin composition, polymer film using the same and circuit board | 广东鸿翔瑞材料科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116457417-A | Resin composition, prepreg, resin sheet, laminate, metal foil-clad laminate, and printed wiring board | 三菱瓦斯化学株式会社 | 2023-07-18 | — | — | CN | claimed |
| CN-104755422-A | Method for producing cyanogen halide, cyanate ester compound and method for producing same, and resin composition | MITSUBISHI GAS CHEMICAL CO | 2015-07-01 | — | — | CN | claimed |
| CN-102618357-B | Sealing and antirust oil composition | PLA AIR FORCE OIL MATERIAL RES INST | 2013-08-21 | — | — | CN | claimed |
| CN-102618357-A | Sealing and antirust oil composition | PLA AIR FORCE OIL MATERIAL RES INST | 2012-08-01 | — | — | CN | claimed |
| US-20110118374-A1 | Method for Preparing a Hard Film or Coating from a Cationically Cross-Linkable/Polymerizable Composition Comprising an Iodonium Borate and Giving Off an Acceptable Odour | BLUESTAR SILICONES FRANCE SAS (FR) | 2011-05-19 | — | — | US | claimed |
| CN-101641422-A | Vinyl-based polymer having silicon and/or tin and organic light emitting diode using the same | CHEIL IND INC KR | 2010-02-03 | — | — | CN | claimed |
| US-6723143-B2 | ABRASIVE PARTICLES OF AN AQUEOUS METAL OXIDE SOL FORMING A COLLOIDAL SUSPENSION OR DISPERSION COMPRISING A NON-DEHYDRATED METAL OXIDE(S); CHEMICALLY REACTIVE WITH THE LOW DIELECTRIC CONSTANT MATERIAL; SPHERES; DIMENSIONALLY STABLE | HONEYWELL INTERNATIONAL INC. | 2004-04-20 | — | — | US | claimed |
| WO-2004015018-A1 | REACTIVE AQUEOUS METAL OXIDE SOLS AS POLISHING SLURRIES FOR LOW DIELECTRIC CONSTANT MATERIALS | HONEYWELL INTERNATIONAL INC. (US) | 2004-02-19 | — | — | WO | claimed |
| US-20030005647-A1 | Reactive aqueous metal oxide sols as polishingslurries for low dielectric constant materials | TOWERY DANIEL | 2003-01-09 | — | — | US | claimed |
| US-6464740-B1 | ABRASIVE BIMODAL METAL OXIDES; DIMENSIONAL STABILITY; CHEMICAL MECHANICAL POLISHING | HONEYWELL INTERNATIONAL INC. | 2002-10-15 | — | — | US | claimed |
| CN-1107141-A | Naphthyl ethers, their preparation, compositions containing them and their use | BASF AG (DE) | 1995-08-23 | — | — | CN | claimed |