Toluene

Toluene

SCHEMBL525532

Cc1ccccc1.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Toluene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL6666244 1.00 ACHE (0.92)
Toluene SCHEMBL16353981 1.00 ACHE (0.92)
Toluene SCHEMBL27770264 1.00
Toluene SCHEMBL8593368 1.00 ACHE (0.92)
Toluene SCHEMBL28796280 1.00 ACHE (0.92)
Toluene SCHEMBL10383356 1.00 ACHE (0.92)
Toluene SCHEMBL3319586 1.00 ACHE (0.92)
Toluene SCHEMBL10657160 0.96 ACHE (0.85)
Toluene SCHEMBL294510 0.96
Toluene SCHEMBL27531376 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120944352-B Bismaleimide modified epoxy resin and preparation method thereof 江苏耀鸿电子有限公司 2026-05-12 CN claimed
CN-116410126-B Ligand, ruthenium complex, preparation method thereof and application of ligand and ruthenium complex in catalyzing alkyne semi-hydrogenation reaction 河北师范大学 2025-05-09 CN claimed
CN-222518603-U Salicylic nitrile photochemical reaction device 重庆长风化学工业有限公司 2025-02-25 CN claimed
CN-119462777-A Preparation method of pentamethyl cyclopentadienyl titanium trichloride 中船(邯郸)派瑞特种气体股份有限公司 2025-02-18 CN claimed
CN-119409682-A 1H-indazole compound and preparation method and application thereof 南京健康产业研究院 2025-02-11 CN claimed
CN-119119146-A New method for preparing 5-deoxidized triacetyl ribose 启东东岳药业有限公司 2024-12-13 CN claimed
CN-118725253-A Novel electronic grade liquid epoxy production process 合肥上华工程设计有限公司 2024-10-01 CN claimed
CN-118562149-A Preparation system and method of biomass-based artificial humic acid 大连理工大学 2024-08-30 CN claimed
CN-118002044-A Production method of indole trimethylol 陕西冠捷生物科技有限公司 2024-05-10 CN claimed
CN-115124430-B Synthesis process of 2,2' -di (trifluoromethyl) diaminobiphenyl 苏利制药科技江阴有限公司 2024-05-07 CN claimed
CN-106831401-A A kind of 3 hydracrylic acid bio-fermented liquid separating-purifying devices and its method of work based on bus marco 徐州工程学院 2017-06-13 CN claimed
CN-106832973-A Sodium lignin sulfonate grafting magnesium-aluminum-based laminar double hydroxide modifying agent, ultraviolet aging resistance SBR modified pitch and preparation method thereof 武汉理工大学 2017-06-13 CN claimed
CN-106800673-A Alkali lignin grafting magnesium-aluminum-based laminar double hydroxide modifying agent, ultraviolet aging resistance SBS modified pitch and preparation method thereof 武汉理工大学 2017-06-06 CN claimed
CN-106700579-A Lignin grafted magnesium aluminum-based layered double hydroxide modifier, anti-ultraviolet ageing asphalt and preparation method thereof 武汉理工大学 2017-05-24 CN claimed
CN-106188037-A A kind of compound based on 1,8-diaza-9-Fluorenone and application thereof 中节能万润股份有限公司 2016-12-07 CN claimed
CN-205549617-U A separation evaporimeter for separating toluene oxidation decomposes liquid 湖北科林博伦新材料有限公司 2016-09-07 CN claimed
CN-105924438-A Organic optoelectronic material with indeno-phenanthroline structure and preparing method and application thereof 中节能万润股份有限公司 2016-09-07 CN claimed
CN-101481608-B Clean fracturing fluid and use thereof UNIV CHINA PETROLEUM 2011-08-10 CN claimed
CN-101481608-A Clean fracturing fluid and use thereof UNIV CHINA PETROLEUM (CN) 2009-07-15 CN claimed
CN-101440057-A Chloridization method for nitrogen heterocyclic butanone isobutene derivatives BEIJING CHARNA CHEMICALS LTD (CN) 2009-05-27 CN claimed