Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | HPD | P32754 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525555 | 0.81 | BRD4 (0.52) | BRD4MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL525732 | 0.74 | ALOX15 (0.42) | BRD4MAOBNPC1ALDH1A1HPGD | |
| SCHEMBL525420 | 0.74 | EGFR (0.43) | MAOBMAOAALDH1A1HPGD | |
| SCHEMBL525548 | 0.74 | KDM4E (0.38) | MAOBMAOAGRM5 | |
| SCHEMBL4095412 | 0.74 | MAOA (0.77) | BRD4MAOBHPDMAOAGSTP1 | |
| SCHEMBL15328748 | 0.72 | BRD4 (1.00) | BRD4HPDCREBBP | |
| SCHEMBL27624293 | 0.72 | MRGPRX4 (0.45) | MAOBPIN1 | |
| SCHEMBL524806 | 0.72 | TGFBR1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3979344 | 0.71 | SMPD1 (0.47) | MAOBPIN1NPC1ALDH1A1RAB9A | |
| SCHEMBL379281 | 0.70 | MAOB (0.67) | MAOBMAOAGSTP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | claimed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | claimed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | claimed |
| EP-2420495-A1 | Novel derivatives useful as antiviral agents | Institut Pasteur (FR) | 2012-02-22 | — | — | EP | claimed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | claimed |
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | disclosed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | disclosed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | disclosed |
| EP-2420495-A1 | Novel derivatives useful as antiviral agents | Institut Pasteur (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | MAVS, IRF3, IFNAR1 | BRD4 1780/4885MAOB 640/4885HPD 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.