Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049802 | 0.85 | L3MBTL1 (0.52) | MCHR1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL786000 | 0.82 | HTR3E (0.54) | HRH3MAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5214643 | 0.82 | MCHR1 (0.59) | HRH3MCHR1ALDH1A1ME3 | |
| SCHEMBL2883836 | 0.81 | DRD2 (0.53) | LTA4HHRH3MAPTHTTKDM4E | |
| SCHEMBL1749032 | 0.80 | HRH3 (0.65) | HRH3MCHR1MAPTHTTKDM4E | |
| SCHEMBL1748880 | 0.80 | HRH3 (0.65) | HRH3MCHR1MAPTHTTKDM4E | |
| SCHEMBL1749597 | 0.80 | HRH3 (0.65) | HRH3MCHR1MAPTHTTKDM4E | |
| SCHEMBL3891049 | 0.79 | LTA4H (0.60) | LTA4HDPP4HRH3MAPTHTT | |
| SCHEMBL13234950 | 0.79 | LTA4H (0.60) | LTA4HDPP4HRH3MAPTHTT | |
| SCHEMBL13202835 | 0.78 | LTA4H (0.61) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| CN-1264821-C | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SUNTORY LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| US-7067533-B2 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| CN-1449493-A | Aminophenoxyacetamide derivatives and pharmaceutical compositions containing them | SUNTORY LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1228367-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001079170-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | LTA4H 4260/4885DPP4 3263/4885HRH3 2569/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | LTA4H 1554/4885DPP4 2604/4885HRH3 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.