Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167012 | 0.84 | ATAD2 (0.56) | DAOATAD2KDM4EALDH1A1HRH4 | |
| SCHEMBL2898417 | 0.83 | ATAD2 (0.54) | DAOATAD2KDM4EALDH1A1HRH4 | |
| Trifluoromethanesulfonic Acid SCHEMBL18692581 | 0.79 | AXL (0.37) | DAOATAD2L3MBTL1KDM4EALOX12 | |
| SCHEMBL27791126 | 0.75 | ATAD2 (0.46) | DAOATAD2KDM4EALDH1A1HRH4 | |
| Isoxazole SCHEMBL29144694 | 0.72 | ATAD2 (0.44) | DAOATAD2KDM4EALDH1A1HRH4 | |
| Quinoxaline SCHEMBL28065589 | 0.72 | ALDH1A1 (0.37) | L3MBTL1KDM4EALDH1A1ALOX12HPGD | |
| Aminothiazole SCHEMBL29250377 | 0.71 | ATAD2 (0.43) | DAOATAD2KDM4EALDH1A1HRH4 | |
| Quinoline SCHEMBL5260404 | 0.70 | ALDH1A1 (0.61) | KDM4EALDH1A1ALOX12HSD17B10 | |
| Quinoline SCHEMBL28462227 | 0.69 | ALDH1A1 (0.59) | KDM4EALDH1A1ALOX12HSD17B10 | |
| Quinoline SCHEMBL28462226 | 0.69 | ALDH1A1 (0.59) | KDM4EALDH1A1ALOX12HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594849-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149500-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-28 | — | — | US | disclosed |
| EP-1594849-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004064741-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC. (US) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149500-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | DAO 4340/4885ATAD2 3087/4885L3MBTL1 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.