Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22407068 | 0.83 | MAOB (0.68) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL22439721 | 0.81 | CYP11B1 (0.48) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL22406928 | 0.81 | CYP11B1 (0.48) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL17996051 | 0.77 | P2RX3 (0.55) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL11544488 | 0.77 | MAOB (0.50) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL5255602 | 0.76 | MAOB (0.52) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL11540801 | 0.75 | MAOB (0.48) | MAOBMAOACYP11B1CYP11B2P2RX3 | |
| SCHEMBL6701425 | 0.75 | CES2 (0.66) | MAOBCYP11B1CYP11B2 | |
| SCHEMBL6701419 | 0.75 | CES2 (0.66) | MAOBCYP11B1CYP11B2 | |
| SCHEMBL30391817 | 0.73 | MAOA (0.46) | MAOBMAOACYP11B1CYP11B2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844993-B1 | PESTICIDAL INDAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-09-26 | — | — | EP | disclosed |
| EP-0844993-A2 | PESTICIDAL INDAZOLE DERIVATIVES | Novartis AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |