Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262274 | 1.00 | ALOX5 (0.35) | ALOX5APPMEN1KMT2AHSD11B1 | |
| SCHEMBL30296278 | 0.79 | ALOX5 (0.41) | ALOX5MEN1KMT2AEPHX1L3MBTL1 | |
| SCHEMBL9071877 | 0.78 | L3MBTL1 (0.41) | ALOX5MEN1KMT2AHSD11B1EPHX1 | |
| SCHEMBL8607828 | 0.77 | THRA (0.40) | EPHX1L3MBTL1 | |
| SCHEMBL2114826 | 0.76 | ALOX5 (0.36) | ALOX5MC4RMC5RMC3RF2 | |
| SCHEMBL2497168 | 0.75 | ALOX5 (0.41) | ALOX5MEN1KMT2AEPHX1L3MBTL1 | |
| SCHEMBL21548898 | 0.75 | ALOX5 (0.41) | ALOX5MEN1KMT2AMC4RMC5R | |
| SCHEMBL6255211 | 0.75 | THRA (0.42) | EPHX1 | |
| SCHEMBL17923271 | 0.75 | HRH4 (0.35) | APPMEN1KMT2A | |
| SCHEMBL27971919 | 0.74 | ADH1A (0.47) | ALOX5MEN1KMT2AHSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |