Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | FABP4 | P15090 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL19640923 | 1.00 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL19640928 | 1.00 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL19640925 | 1.00 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7783095 | 0.98 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Adipic Acid SCHEMBL27765050 | 0.93 | CYP2D6 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL722130 | 0.91 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL20835366 | 0.91 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL22204639 | 0.91 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL20835361 | 0.91 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL4139803 | 0.91 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659580-B1 | CLEANSER COMPOSITION | KAO CORP (JP) | 2025-11-05 | — | — | EP | claimed |
| US-11628130-B2 | Cleanser composition | KAO CORPORATION (JP) | 2023-04-18 | — | — | US | claimed |
| CN-110958872-B | Cleaning agent composition | 花王株式会社 | 2023-03-14 | — | — | CN | claimed |
| CN-109549860-B | Preparation method of positively charged liposome and charged liposome | J网络公司 | 2022-06-07 | — | — | CN | claimed |
| US-20210145720-A1 | CLEANSER COMPOSITION | KAO CORPORATION (JP) | 2021-05-20 | — | — | US | claimed |
| US-11000477-B2 | Preparing method for positively-electrified charged niosome, and charged niosome | J-NETWORK, INC. (US) | 2021-05-11 | — | — | US | claimed |
| EP-3659580-A1 | CLEANSER COMPOSITION | Kao Corporation (JP) | 2020-06-03 | — | — | EP | claimed |
| CN-110958872-A | Cleaning agent composition | 花王株式会社 | 2020-04-03 | — | — | CN | claimed |
| US-20190091153-A1 | PREPARING METHOD FOR POSITIVELY-ELECTRIFIED CHARGED NIOSOME, AND CHARGED NIOSOME | J-NETWORK, INC. (US) | 2019-03-28 | — | — | US | claimed |
| EP-3459525-A1 | PREPARING METHOD FOR POSITIVELY-ELECTRIFIED CHARGED NIOSOME, AND CHARGED NIOSOME | J-Network, Inc. (US) | 2019-03-27 | — | — | EP | claimed |
| JP-63280403-A | — | — | None | — | — | JP | disclosed |
| CN-122005622-A | Composition for improving, preventing or treating vaginitis or vulvitis comprising lactobacillus salivarius HHuMin-U | 比菲德股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12582590-B2 | Transparent liquid composition and cosmetic containing said composition | SEIWA KASEI COMPANY, LIMITED (JP) | 2026-03-24 | — | — | US | disclosed |
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | disclosed |
| EP-3659580-B1 | CLEANSER COMPOSITION | KAO CORP (JP) | 2025-11-05 | — | — | EP | disclosed |
| US-5603861-A | NONAQUEOUS; DIELECTRIC | TONEN CORPORATION (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0743847-A1 | HAIR COSMETIC COMPOSITION | Kao Corporation (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0671460-A1 | ELECTROVISCOUS FLUID | Tonen Corporation (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995020375-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 1995-08-03 | — | — | WO | disclosed |
| JP-S63280403-A | CONDUCTIVE MAGNETIC FLUID COMPOSITING AND MANUFACTURE THEREOF | NIPPON SEIKO KK | 1988-11-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145720-A1 | CLEANSER COMPOSITION | ADH1C, WASHC4, AP2S1 | GPR84 694/4885PPARG 1669/4885PPARD 2124/4885 |
| US-11628130-B2 | Cleanser composition | ADH1C, SMURF1, DEGS1 | GPR84 745/4885PPARG 1454/4885PPARD 1600/4885 |
| US-12582590-B2 | Transparent liquid composition and cosmetic containing said composition | GK, CUTA, GHDC | GPR84 1497/4885PPARG 117/4885PPARD 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.