Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267951 | 0.85 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHSD17B10RAB9A | |
| SCHEMBL5266262 | 0.72 | NOTUM (0.53) | ALDH1A1KDM4ERAB9ATSHRSMN1; SMN2 | |
| SCHEMBL2871930 | 0.72 | ALDH1A1 (0.50) | ALOX15ALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL29354014 | 0.72 | ALDH1A1 (0.50) | ALOX15ALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL8630238 | 0.70 | RAB9A (0.57) | ALDH1A1KDM4EHSD17B10RAB9AHPGD | |
| SCHEMBL8629170 | 0.70 | CASP3 (0.46) | ALDH1A1KDM4EHSD17B10RAB9ACYP1A2 | |
| SCHEMBL537002 | 0.70 | ALDH1A1 (0.52) | ALOX15ALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL27506937 | 0.70 | ALDH1A1 (0.48) | ALOX15ALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL29538643 | 0.70 | ALDH1A1 (0.48) | ALOX15ALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL4718626 | 0.69 | BRD4 (0.43) | ALDH1A1KDM4EHSD17B10RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |