Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294933 | 0.87 | CCR2 (0.55) | CCR2APEX1ALDH1A1TDP1MEN1 | |
| SCHEMBL27964872 | 0.75 | CCR2 (0.58) | CCR2APEX1ALDH1A1TDP1MEN1 | |
| SCHEMBL21313807 | 0.75 | CCR2 (0.52) | CCR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3255649 | 0.72 | CCR2 (0.55) | CCR2APEX1ALDH1A1TDP1TSHR | |
| SCHEMBL28293100 | 0.71 | CCR2 (0.46) | CCR2ALDH1A1TDP1MEN1KMT2A | |
| Acetic Acid SCHEMBL28750519 | 0.71 | L3MBTL1 (0.44) | CCR2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7993476 | 0.69 | CCR2 (0.64) | CCR2APEX1ALDH1A1TDP1MEN1 | |
| SCHEMBL28205828 | 0.67 | ALDH1A1 (0.47) | APEX1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6807284 | 0.67 | GPR35 (0.61) | ALDH1A1TDP1TSHRKDM4EGPR35 | |
| SCHEMBL3560535 | 0.67 | NOD2 (0.48) | CCR2ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841762-A1 | SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | Aventis Pharma S.A. (FR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006061493-A1 | SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | AVENTIS PHARMA S.A. (FR) | 2006-06-15 | — | — | WO | disclosed |