SCHEMBL5266548

SCHEMBL5266548

CCCC(C)[Si](OC(C)=O)(OC(C)=O)OC(C)=O.CCCC(C)[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.40
MTNR1B P49286 6/20 0.40
POLB P06746 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NPY5R Q15761 1/20 0.35
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GPR88 Q9GZN0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397780 0.86 LMNA (0.38) POLBALDH1A1LMNASMN1; SMN2PPARG
SCHEMBL3200306 0.82 CHRM1 (0.39) ALDH1A1LMNATDP1TSHRHSD17B10
SCHEMBL5724915 0.74 AKR1C3 (0.36) MTNR1AMTNR1BLMNAPPARGNPC1
SCHEMBL5724910 0.74 AKR1C3 (0.36) MTNR1AMTNR1BLMNAPPARGNPC1
SCHEMBL18496505 0.74 MTNR1A (0.42) MTNR1AMTNR1BPOLBALDH1A1LMNA
SCHEMBL432009 0.73 LMNA (0.39) MTNR1AMTNR1BALDH1A1LMNANPY5R
SCHEMBL4455176 0.73 TDP1 (0.42) MTNR1AMTNR1BPOLBPPARGTDP1
SCHEMBL25263655 0.73 MTNR1A (0.44) MTNR1AMTNR1BALDH1A1LMNATDP1
SCHEMBL5724911 0.72 HPGD (0.37) MTNR1AMTNR1BALDH1A1LMNASMN1; SMN2
SCHEMBL28404949 0.72 PPARG (0.41) POLBALDH1A1LMNASMN1; SMN2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1837086-A2 Low dielectric materials and methods for making same Air Products and Chemicals, Inc. (US) 2007-09-26 EP disclosed
EP-1464410-A1 Low dielectric materials and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-10-06 EP disclosed