Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5270309 | 0.99 | FFAR4 (0.34) | FFAR4PPARDHTR2APTPN5GCK | |
| SCHEMBL5337927 | 0.87 | HTR2A (0.34) | FFAR4PPARDHTR2AGCK | |
| SCHEMBL5267628 | 0.81 | PPARD (0.39) | PPARDFFAR1RXRARXRBRXRG | |
| SCHEMBL5502236 | 0.79 | FFAR1 (0.38) | PPARDFFAR1 | |
| SCHEMBL5501032 | 0.79 | THRA (0.40) | FFAR4PPARDPTPN5RXRARXRB | |
| SCHEMBL5270824 | 0.79 | PTPN1 (0.37) | PPARDPTPN5 | |
| SCHEMBL5502096 | 0.78 | BRD4 (0.39) | PPARDSCN9A | |
| SCHEMBL5505765 | 0.78 | PTGDR2 (0.44) | PPARDFFAR1RXRARXRBRXRG | |
| SCHEMBL5507776 | 0.77 | RXRA (0.42) | PPARDGCKFFAR1RXRARXRB | |
| SCHEMBL5507821 | 0.76 | ACACB (0.39) | FFAR4FFAR1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |