Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 10/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507776 | 0.91 | RXRA (0.42) | PPARDRXRARXRBRXRGTHRB | |
| SCHEMBL5504469 | 0.90 | PPARD (0.41) | PTGDR2PPARDTHRBSCN8ASCN10A | |
| SCHEMBL5502236 | 0.90 | FFAR1 (0.38) | PTGDR2PPARDTHRBFFAR1 | |
| SCHEMBL5505980 | 0.85 | PTGS2 (0.43) | — | |
| SCHEMBL5517204 | 0.81 | TOP1 (0.34) | PTGDR2PPARDRXRARXRBRXRG | |
| SCHEMBL5267628 | 0.81 | PPARD (0.39) | PPARDRXRARXRBRXRGMAPT | |
| SCHEMBL5502096 | 0.80 | BRD4 (0.39) | PPARDRAB9A | |
| SCHEMBL5502760 | 0.78 | MAP2 (0.39) | PTGDR2MAPTKDM4EFFAR1 | |
| Water SCHEMBL5270309 | 0.77 | FFAR4 (0.34) | PTGDR2PPARDFFAR1 | |
| SCHEMBL5502589 | 0.77 | EGLN1 (0.39) | PPARDMAPTTHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |