Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505765 | 0.90 | PTGDR2 (0.44) | FFAR1THRBPPARDPTGDR2 | |
| SCHEMBL5507776 | 0.89 | RXRA (0.42) | FFAR1THRBPPARDPPARAPPARG | |
| SCHEMBL5504469 | 0.88 | PPARD (0.41) | FFAR1THRBPPARDPPARAPTGDR2 | |
| SCHEMBL5507821 | 0.88 | ACACB (0.39) | FFAR1FNTAFNTB | |
| SCHEMBL5503574 | 0.84 | MEN1 (0.39) | FFAR1THRBPPARD | |
| SCHEMBL5267628 | 0.82 | PPARD (0.39) | FFAR1PPARDPPARA | |
| SCHEMBL5501032 | 0.82 | THRA (0.40) | THRBPPARDPPARAPPARG | |
| SCHEMBL5502096 | 0.81 | BRD4 (0.39) | PPARD | |
| SCHEMBL5266845 | 0.79 | FFAR4 (0.34) | FFAR1PPARD | |
| Water SCHEMBL5270309 | 0.79 | FFAR4 (0.34) | FFAR1PPARDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |