Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.30 |
| ▸ | MYLK | Q15746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929889 | 0.77 | NPSR1 (0.42) | RAB9ANPC1L3MBTL1FFAR1KMT2A | |
| SCHEMBL6033646 | 0.77 | TRPM8 (0.38) | SMN1; SMN2LMNAKMT2A | |
| SCHEMBL5271205 | 0.71 | KCNA5 (0.36) | RAB9ANPC1L3MBTL1SMN1; SMN2KDR | |
| SCHEMBL743478 | 0.67 | NPSR1 (0.45) | P2RX7RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5880701 | 0.67 | P2RX7 (0.42) | P2RX7RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7982618 | 0.66 | ALDH1A1 (0.49) | RAB9ANPC1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL10464974 | 0.65 | NPSR1 (0.42) | RAB9ANPC1L3MBTL1KMT2APARP1 | |
| Urea SCHEMBL9618576 | 0.63 | P2RX7 (0.55) | P2RX7RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7940014 | 0.63 | HDAC6 (0.41) | RAB9ANPC1KMT2A | |
| SCHEMBL27551941 | 0.63 | HTT (0.47) | RAB9ANPC1L3MBTL1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248713-B1 | OLIGOPEPTIDE FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | BIOGEN, INC. | 2001-06-19 | — | — | US | claimed |
| EP-0842196-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2007-11-21 | — | — | EP | disclosed |
| CN-1195778-C | cell adhesion inhibitors | BIOGEN INC (US) | 2005-04-06 | — | — | CN | disclosed |
| CN-1193325-A | cell adhesion inhibitors | BIOGEN INC (US) | 1998-09-16 | — | — | CN | disclosed |