Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266813 | 0.85 | MEN1 (0.35) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13816863 | 0.82 | KMT2A (0.38) | L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL5267751 | 0.81 | NPC1 (0.56) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5267069 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2AHPGD | |
| SCHEMBL5271053 | 0.81 | L3MBTL1 (0.51) | L3MBTL1HPGD | |
| SCHEMBL5271036 | 0.80 | KMT2A (0.43) | L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL5269043 | 0.80 | KMT2A (0.41) | MEN1KMT2AHPGD | |
| SCHEMBL5268091 | 0.80 | LMNA (0.55) | L3MBTL1KMT2AHPGD | |
| SCHEMBL5271765 | 0.79 | ALDH1A1 (0.48) | L3MBTL1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL5274022 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |