Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273232 | 0.81 | L3MBTL1 (0.36) | HPGDMEN1KMT2A | |
| SCHEMBL5270110 | 0.80 | KCNK3 (0.42) | ALDH1A1HPGDSMN1; SMN2GAAPIK3C3 | |
| SCHEMBL5268887 | 0.79 | KCNK3 (0.39) | ALDH1A1HPGDGAAPIK3C3KCNK3 | |
| SCHEMBL5269236 | 0.78 | MMP2 (0.41) | ALDH1A1HPGDMEN1KMT2ANAMPT | |
| SCHEMBL5266813 | 0.78 | MEN1 (0.35) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5268756 | 0.77 | LMNA (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5265490 | 0.76 | HTR6 (0.44) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13816863 | 0.76 | KMT2A (0.38) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL5267751 | 0.74 | NPC1 (0.56) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL5271053 | 0.74 | L3MBTL1 (0.51) | HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |