Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268091 | 0.89 | LMNA (0.55) | L3MBTL1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL5266983 | 0.88 | RXFP1 (0.49) | NPC1RAB9AL3MBTL1HPGDGAA | |
| SCHEMBL5274022 | 0.88 | L3MBTL1 (0.46) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5271765 | 0.88 | ALDH1A1 (0.48) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5271053 | 0.88 | L3MBTL1 (0.51) | L3MBTL1HPGDGAAHSD17B10LMNA | |
| SCHEMBL5265743 | 0.87 | ALDH1A1 (0.53) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5269971 | 0.86 | L3MBTL1 (0.50) | L3MBTL1KMT2AHPGDGAAMEN1 | |
| SCHEMBL5271036 | 0.83 | KMT2A (0.43) | NPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5273212 | 0.82 | ALDH1A1 (0.47) | L3MBTL1KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL5273232 | 0.81 | L3MBTL1 (0.36) | NPC1RAB9AL3MBTL1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |