Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267751 | 0.89 | NPC1 (0.56) | LMNAGAAKMT2AHSD17B10L3MBTL1 | |
| SCHEMBL5266983 | 0.86 | RXFP1 (0.49) | POLBGAAHSD17B10L3MBTL1MAPT | |
| SCHEMBL5274022 | 0.86 | L3MBTL1 (0.46) | LMNAPOLBGAAKMT2AHSD17B10 | |
| SCHEMBL5271765 | 0.86 | ALDH1A1 (0.48) | KMT2AHSD17B10L3MBTL1ALDH1A1MAPT | |
| SCHEMBL5271053 | 0.86 | L3MBTL1 (0.51) | LMNAPOLBGAAHSD17B10L3MBTL1 | |
| SCHEMBL5265743 | 0.85 | ALDH1A1 (0.53) | LMNAPOLBGAAKMT2AL3MBTL1 | |
| SCHEMBL5269971 | 0.84 | L3MBTL1 (0.50) | LMNAPOLBGAAKMT2AHSD17B10 | |
| SCHEMBL5273212 | 0.83 | ALDH1A1 (0.47) | LMNAPOLBGAAKMT2AHSD17B10 | |
| SCHEMBL5269337 | 0.82 | SLC40A1 (0.49) | LMNAPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL5269927 | 0.81 | LMNA (0.49) | LMNAKEAP1NFE2L2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |