Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000925 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL2399274 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29897041 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30393982 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL756338 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL27469947 | 0.80 | MEN1 (0.60) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4463471 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL30002774 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8682628 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5270788 | 0.78 | RAB9A (0.57) | ALDH1A1KDM4EKMT2ACAPN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183412-B2 | Ester or amide derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |
| CN-1735599-A | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands | BOEHRINGER INGELHEIM PHARMA (US) | 2006-02-15 | — | — | CN | disclosed |
| CN-1212317-C | Novel ester or amide derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2005-07-27 | — | — | CN | disclosed |
| US-20050090497-A1 | Novel ester or amide derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2005-04-28 | — | — | US | disclosed |
| US-6822098-B2 | CARBOCYCLIC CARBO, OXO AMINES SUCH AS N-HEPTYL-3-METHYL-4-OXO -1,4-DIHYDROQUINOLINE-2-CARBOXAMIDE, USED FOR PROPHYLAXIS OF GASTROINTERSTINAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20040019214-A1 | Novel ester or amide derivatives | ASTELLAS PHARMA INC. (JP) | 2004-01-29 | — | — | US | disclosed |
| CN-1449384-A | Novel ester or amide derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| EP-1314726-A1 | NOVEL ESTER OR AMIDE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019214-A1 | Novel ester or amide derivatives | CYP3A7, UGT2B7, NAT1 | ALDH1A1 122/4885KDM4E 1866/4885HPGD 1330/4885 |
| US-20050090497-A1 | Novel ester or amide derivatives | CYP3A7, CYP7A1, UGT2B7 | ALDH1A1 117/4885KDM4E 2052/4885HPGD 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.