SCHEMBL527377

SCHEMBL527377

C[Si](C)(C)O[Si](C)(CC(=O)O)CC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
CTH P32929 1/20 0.33
CBS P35520 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL526437 0.77 LMNA (0.36) TSHRFFAR3ALDH1A1LMNA
SCHEMBL512417 0.74 FFAR3 (0.35) TSHRFFAR3LMNA
SCHEMBL14518486 0.70 FFAR3 (0.32) TSHRFFAR3
SCHEMBL442427 0.69
SCHEMBL632284 0.69 FFAR3 (0.41) TSHRFFAR3ALDH1A1LMNAAPEX1
SCHEMBL29065871 0.69 FFAR3 (0.41) TSHRFFAR3ALDH1A1LMNAAPEX1
SCHEMBL10948958 0.67
SCHEMBL9042815 0.67
SCHEMBL8415864 0.67
SCHEMBL4967244 0.67 TSHR (0.38) TSHRFFAR3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598589-A1 A COMPOSITION FOR COATING OVER A PHOTORESIST PATTERN AZ Electronic Materials USA Corp. (US) 2013-06-05 EP disclosed
WO-2012014059-A1 A COMPOSITION FOR COATING OVER A PHOTORESIST PATTERN AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-02-02 WO disclosed