Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280576 | 0.89 | TERT (0.43) | CA1CA2TERTHDAC1MEN1 | |
| SCHEMBL5273386 | 0.86 | ENPP2 (0.46) | CA1CA2LTA4HHDAC1MEN1 | |
| SCHEMBL7870277 | 0.79 | PGK1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19240371 | 0.76 | KIF11 (0.59) | CA1CA2POLBMEN1KMT2A | |
| SCHEMBL2030830 | 0.74 | FDPS (0.47) | TP53MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL5859053 | 0.73 | PTPN5 (0.46) | — | |
| SCHEMBL6421418 | 0.73 | EPHX2 (0.45) | CA1CA2POLBMEN1KMT2A | |
| SCHEMBL13356394 | 0.73 | EPHX2 (0.63) | CA1CA2POLBMEN1KMT2A | |
| SCHEMBL8470305 | 0.72 | PGK1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2382743 | 0.72 | TSHR (0.43) | CA1HDAC1CA12MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860113-A1 | Ectonucleotidase inhibitors | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-28 | — | — | EP | disclosed |