Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273386 | 0.92 | ENPP2 (0.46) | TP53ALDH1A1MAPTENPP2DGAT2 | |
| SCHEMBL5277259 | 0.89 | CA1 (0.45) | TERTTP53ALDH1A1MAPTENPP2 | |
| SCHEMBL23483448 | 0.77 | KIF11 (0.56) | TERTMAPTHDAC1SMN1; SMN2NPC1 | |
| SCHEMBL7870277 | 0.76 | PGK1 (0.44) | ALDH1A1MEN1PKMKMT2APTPN1 | |
| SCHEMBL22754961 | 0.76 | TERT (0.50) | TERTTP53ALDH1A1MAPTHPGD | |
| SCHEMBL5776995 | 0.74 | MAPT (0.43) | TP53ALDH1A1MAPTHDAC1NPC1 | |
| SCHEMBL8322074 | 0.72 | HDAC3 (0.66) | TERTTP53ALDH1A1MAPTHPGD | |
| SCHEMBL2030830 | 0.72 | FDPS (0.47) | TP53ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6660579 | 0.72 | POLB (0.68) | TERTTP53ALDH1A1HDAC1CA12 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.71 | PTPN1 (0.52) | ALDH1A1HDAC1SMN1; SMN2MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860113-A1 | Ectonucleotidase inhibitors | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-28 | — | — | EP | disclosed |