Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038154 | 0.76 | SMO (0.40) | TPSAB1TPSD1TPSG1MAPTKMT2A | |
| SCHEMBL5287833 | 0.74 | LMNA (0.43) | LMNAMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL5277959 | 0.70 | CHRM4 (0.42) | TPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL5281643 | 0.65 | GPR119 (0.49) | — | |
| SCHEMBL5291871 | 0.65 | FAAH (0.51) | ALDH1A1KMT2AHDAC3MEN1 | |
| SCHEMBL5280999 | 0.65 | POLB (0.50) | TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL5277951 | 0.65 | GRIN2B (0.43) | TPSAB1TPSD1TPSG1ALDH1A1KMT2A | |
| SCHEMBL5282980 | 0.64 | CHRM4 (0.42) | TPSAB1TPSD1TPSG1LMNA | |
| SCHEMBL5279858 | 0.64 | GPR119 (0.44) | — | |
| SCHEMBL5292648 | 0.64 | L3MBTL1 (0.49) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |