Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277959 | 0.89 | CHRM4 (0.42) | CHRM4KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL5291871 | 0.81 | FAAH (0.51) | CHRM4KMT2ASMN1; SMN2 | |
| SCHEMBL5282679 | 0.79 | ALDH1A1 (0.45) | CHRM4KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL5279924 | 0.78 | KMT2A (0.48) | CHRM4KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL5282756 | 0.78 | RAB9A (0.50) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5292648 | 0.77 | L3MBTL1 (0.49) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5289399 | 0.77 | LMNA (0.47) | CHRM4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5280999 | 0.77 | POLB (0.50) | CHRM4TPSAB1TPSD1TPSG1 | |
| SCHEMBL5280644 | 0.76 | TPSAB1 (0.35) | KMT2ATPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL5279075 | 0.75 | WNT3 (0.45) | SMOCHRM4KMT2ATPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | SMO 1069/4885CHRM4 3413/4885KMT2A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.