Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281910 | 0.86 | NR1I2 (0.55) | SMN1; SMN2PTPN1KMT2ATSHRMEN1 | |
| SCHEMBL5283944 | 0.81 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL697566 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1KMT2ATSHRMMP2 | |
| SCHEMBL7850104 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL10602149 | 0.73 | MEN1 (0.41) | SMN1; SMN2ALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL20657050 | 0.73 | KMT2A (0.76) | SMN1; SMN2ALDH1A1KMT2ATSHRMMP2 | |
| SCHEMBL18358944 | 0.72 | MMP2 (0.59) | SMN1; SMN2ALDH1A1KMT2ATSHRMMP2 | |
| SCHEMBL18263620 | 0.70 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1KMT2AMMP2MMP9 | |
| SCHEMBL15570178 | 0.69 | OPRK1 (0.34) | KMT2AMEN1 | |
| SCHEMBL6937307 | 0.69 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | SMN1; SMN2 3894/4885ALDH1A1 2972/4885PTPN1 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.