Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.66 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101490 | 0.85 | RAB9A (0.66) | ALDH1A1PTPN1PTPN6PTPN11RAB9A | |
| SCHEMBL5286157 | 0.84 | NR1I2 (0.76) | ALDH1A1PTPN1RAB9ASMN1; SMN2NR1I2 | |
| SCHEMBL10194271 | 0.83 | RAB9A (0.64) | ALDH1A1PTPN1PTPN6PTPN11RAB9A | |
| SCHEMBL697566 | 0.82 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2MMP2MMP9TSHR | |
| SCHEMBL5281872 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1PTPN1PTPN6PTPN11SMN1; SMN2 | |
| SCHEMBL24445723 | 0.81 | GAA (0.63) | ALDH1A1PTPN1PTPN6PTPN11RAB9A | |
| SCHEMBL18358944 | 0.80 | MMP2 (0.59) | ALDH1A1SMN1; SMN2MMP2MMP9TSHR | |
| SCHEMBL7850104 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1PTPN1PTPN6PTPN11SMN1; SMN2 | |
| SCHEMBL5568657 | 0.79 | NR1I2 (0.65) | ALDH1A1PTPN1NR1I2MAPK1TSHR | |
| SCHEMBL10956866 | 0.78 | NR1I2 (0.64) | ALDH1A1PTPN1SMN1; SMN2NR1I2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | ALDH1A1 2972/4885PTPN1 2060/4885PTPN6 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.