Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445723 | 0.83 | GAA (0.63) | RAB9APOLBNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5283944 | 0.83 | ALDH1A1 (0.71) | RAB9AALDH1A1SMN1; SMN2LMNAPTPN1 | |
| SCHEMBL28101490 | 0.82 | RAB9A (0.66) | RAB9APOLBNPSR1ALDH1A1PTPN1 | |
| SCHEMBL10194274 | 0.81 | ALDH1A1 (0.58) | RAB9APOLBNPSR1USP2ALDH1A1 | |
| SCHEMBL8420037 | 0.80 | RAB9A (0.42) | RAB9APOLBNPSR1USP2ALDH1A1 | |
| SCHEMBL22400033 | 0.79 | HSD17B1 (0.43) | RAB9APOLBALDH1A1MEN1KMT2A | |
| SCHEMBL2696214 | 0.77 | POLB (0.61) | POLBNPSR1USP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10194302 | 0.76 | MEN1 (0.69) | USP2ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL13603837 | 0.75 | TSHR (0.42) | RAB9AALDH1A1MEN1KMT2AHTT | |
| SCHEMBL18460499 | 0.72 | RECQL (0.64) | POLBNPSR1USP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173699-B2 | Compounds for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100190767-A1 | Compounds for the treatment of inflammatory diseases | ANDERSKEWITZ RALF | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190767-A1 | Compounds for the treatment of inflammatory diseases | MALT1, IL1B, RORC | RAB9A 1909/4885POLB 1793/4885NPSR1 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.