Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246343 | 0.94 | MEN1 (0.55) | ADAMTS5KMT2ASMN1; SMN2CHRM4MEN1 | |
| SCHEMBL4245175 | 0.90 | FAAH (0.58) | KMT2ASMN1; SMN2CHRM4MEN1FAAH | |
| SCHEMBL4239342 | 0.90 | SMN1; SMN2 (0.63) | KMT2ASMN1; SMN2MEN1LTB4RLTB4R2 | |
| SCHEMBL4244741 | 0.89 | SLC6A5 (0.53) | KMT2ASMN1; SMN2CHRM4MEN1LTB4R | |
| SCHEMBL4244550 | 0.87 | EPHX2 (0.54) | KMT2APKMSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4251982 | 0.85 | DGAT1 (0.54) | KMT2ASMN1; SMN2CHRM4MEN1FAAH | |
| SCHEMBL4247871 | 0.84 | KMT2A (0.62) | ADAMTS5KMT2ASMN1; SMN2MEN1FAAH | |
| SCHEMBL5284883 | 0.84 | FAAH (0.62) | KMT2ASMN1; SMN2MEN1FAAHMAPT | |
| SCHEMBL5182248 | 0.83 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2CHRM4MEN1LTB4R | |
| SCHEMBL4239616 | 0.82 | FAAH (0.61) | KMT2AMEN1FAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |