Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325610 | 0.91 | MEN1 (0.39) | HSD17B10PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL5321670 | 0.88 | ALOX15 (0.44) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5325660 | 0.85 | ALDH1A1 (0.48) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5457973 | 0.77 | — | — | |
| SCHEMBL5328796 | 0.74 | DNM1 (0.45) | KDM4EALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5325599 | 0.72 | KDM4E (0.38) | HSD17B10PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL18931673 | 0.72 | MEN1 (0.36) | HSD17B10PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL14622410 | 0.71 | MAPT (0.43) | PRMT5WDR77KDM4EALDH1A1HPGD | |
| SCHEMBL5328610 | 0.70 | MEN1 (0.36) | HSD17B10PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL5321659 | 0.70 | ALOX15 (0.43) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |