Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285676 | 0.91 | HSD17B10 (0.36) | MEN1KMT2AMAPK1EGFRTYMS | |
| SCHEMBL5321670 | 0.90 | ALOX15 (0.44) | MEN1KMT2AMAPK1EGFRTYMS | |
| SCHEMBL5325660 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL5325599 | 0.81 | KDM4E (0.38) | MEN1KMT2AMAPK1PRMT5WDR77 | |
| SCHEMBL18931673 | 0.81 | MEN1 (0.36) | MEN1KMT2AMAPK1EGFRTYMS | |
| SCHEMBL5328610 | 0.79 | MEN1 (0.36) | MEN1KMT2AMAPK1EGFRTYMS | |
| SCHEMBL5328796 | 0.73 | DNM1 (0.45) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5321659 | 0.71 | ALOX15 (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL14622410 | 0.70 | MAPT (0.43) | MEN1KMT2AMAPK1PRMT5WDR77 | |
| SCHEMBL5323186 | 0.68 | MAPT (0.51) | MEN1KMT2AMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |