Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322162 | 0.91 | SLC6A7 (0.41) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL5285676 | 0.85 | HSD17B10 (0.36) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL5325651 | 0.84 | LMNA (0.47) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL5457973 | 0.71 | — | — | |
| SCHEMBL14622908 | 0.69 | DRD2 (0.38) | — | |
| SCHEMBL11104845 | 0.68 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL12575384 | 0.68 | MAPT (0.75) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL5328796 | 0.67 | DNM1 (0.45) | ALDH1A1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11108098 | 0.66 | LMNA (0.63) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL609364 | 0.66 | LMNA (1.00) | ALDH1A1MAPTLMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |