Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | UBE2N | P61088 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289888 | 0.85 | GRM4 (0.43) | GRM4ALDH1A1 | |
| SCHEMBL5297694 | 0.80 | PLCG1 (0.44) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5291133 | 0.74 | HPGD (0.43) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5295830 | 0.74 | L3MBTL1 (0.32) | POLB | |
| SCHEMBL5306337 | 0.74 | TXNRD1 (0.49) | MAPTTP53SMN1; SMN2GRM4ALDH1A1 | |
| SCHEMBL5294347 | 0.74 | ALDH1A1 (0.42) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5308680 | 0.73 | ALDH1A1 (0.43) | KMT2AMEN1MAPTTP53RAB9A | |
| SCHEMBL5293941 | 0.72 | TXNRD1 (0.43) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL5298909 | 0.71 | POLB (0.45) | KMT2AMAPTTP53POLBGRM4 | |
| SCHEMBL5290295 | 0.71 | MRGPRX4 (0.43) | KMT2AMEN1TP53SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |