Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528635 | 0.85 | ALDH1A1 (0.43) | ALDH1A1NPSR1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL12505329 | 0.75 | MAPT (0.44) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL529539 | 0.72 | MAPT (0.44) | ALDH1A1NPSR1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL24497695 | 0.70 | CYP2C9 (0.50) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL528892 | 0.69 | MAPT (0.41) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL529036 | 0.69 | NPSR1 (0.41) | NPSR1SMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL29096230 | 0.68 | CA12 (0.54) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL31257110 | 0.68 | CA12 (0.52) | ALDH1A1MAPT | |
| SCHEMBL528821 | 0.67 | L3MBTL1 (0.44) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL83318 | 0.66 | CA12 (0.53) | ALDH1A1NPSR1KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |