Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529554 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTPKM | |
| SCHEMBL529036 | 0.79 | NPSR1 (0.41) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL12505329 | 0.74 | MAPT (0.44) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL529539 | 0.71 | MAPT (0.44) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL24497695 | 0.69 | CYP2C9 (0.50) | ALDH1A1KDM4ESMN1; SMN2KMT2APKM | |
| SCHEMBL528892 | 0.68 | MAPT (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL528821 | 0.66 | L3MBTL1 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL83318 | 0.65 | CA12 (0.53) | ALDH1A1KDM4ERAB9AMAPTMEN1 | |
| SCHEMBL29352597 | 0.65 | CA12 (0.53) | ALDH1A1KDM4ERAB9AMAPTMEN1 | |
| SCHEMBL8943599 | 0.65 | LMNA (0.45) | ALDH1A1KDM4ERAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |