Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529036 | 0.82 | NPSR1 (0.41) | MAPTNPSR1POLBESR1GAA | |
| SCHEMBL12505329 | 0.80 | MAPT (0.44) | MAPTNPSR1ALDH1A1RECQLLMNA | |
| SCHEMBL528821 | 0.79 | L3MBTL1 (0.44) | MAPTNPSR1POLBESR1ALDH1A1 | |
| SCHEMBL529539 | 0.76 | MAPT (0.44) | MAPTNPSR1ALDH1A1GAALMNA | |
| SCHEMBL21101926 | 0.69 | LMNA (0.42) | MAPTNPSR1ALDH1A1RECQLLMNA | |
| SCHEMBL528260 | 0.69 | ALDH1A1 (0.39) | MAPTNPSR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL529554 | 0.69 | ALDH1A1 (0.46) | MAPTNPSR1POLBALDH1A1GAA | |
| SCHEMBL528635 | 0.68 | ALDH1A1 (0.43) | MAPTNPSR1ALDH1A1GAALMNA | |
| SCHEMBL2634649 | 0.68 | KMT2A (0.50) | NPSR1POLBESR1ALDH1A1L3MBTL1 | |
| SCHEMBL31201797 | 0.67 | ESR1 (0.45) | ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |