Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505329 | 0.84 | MAPT (0.44) | MAPTNPSR1HTTALDH1A1KDM4E | |
| SCHEMBL528892 | 0.76 | MAPT (0.41) | MAPTNPSR1HTTALDH1A1KDM4E | |
| SCHEMBL529036 | 0.76 | NPSR1 (0.41) | MAPTNPSR1HTTLMNAGAA | |
| SCHEMBL528821 | 0.74 | L3MBTL1 (0.44) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL21375770 | 0.73 | LMNA (0.48) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL20210285 | 0.73 | ALDH1A1 (0.38) | MAPTNPSR1HTTALDH1A1KDM4E | |
| SCHEMBL21101926 | 0.72 | LMNA (0.42) | MAPTNPSR1HTTALDH1A1KDM4E | |
| SCHEMBL528260 | 0.72 | ALDH1A1 (0.39) | MAPTNPSR1HTTALDH1A1KDM4E | |
| SCHEMBL529554 | 0.72 | ALDH1A1 (0.46) | MAPTNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL528635 | 0.71 | ALDH1A1 (0.43) | MAPTNPSR1HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |