SCHEMBL5298071

SCHEMBL5298071

O=S(=O)(Cl)Cc1onc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
CYP3A4 P08684 1/20 0.36
BLM P54132 1/20 0.36
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3229873 0.84 LMNA (0.40) MAOBCA12CA1CA2LMNA
SCHEMBL2920597 0.83 CA2 (0.54) MAOBCA12CA1CA2LMNA
Ammonia Solution, Strong SCHEMBL5291514 0.83 LMNA (0.39) MAOBCA12CA1CA2LMNA
SCHEMBL5288050 0.81 CYP3A4 (0.44) MAOBCA12CA1CA2LMNA
SCHEMBL11919171 0.72 PTGS1 (0.46) SMN1; SMN2ALDH1A1POLBHPGDGPR3
SCHEMBL7002086 0.72 LOXL2 (0.42) MAOBCA12CA1CA2LMNA
SCHEMBL5044710 0.72 ELANE (0.41) MAOBCA12CA1CA2LMNA
SCHEMBL8772757 0.71 ALDH1A1 (0.37) MAOBCA12CA1CA2LMNA
SCHEMBL1027461 0.70 SMN1; SMN2 (0.43) LMNASMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL8772908 0.69 ALDH1A1 (0.37) LMNASMN1; SMN2ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007016209-A2 PURE 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID SODIUM SALT AND PURIFICATION PROCESS TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-02-08 WO claimed
WO-2007016208-A2 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID AMMONIUM SALT TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-02-08 WO claimed
WO-2007016208-A3 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID AMMONIUM SALT TEVA PHARMA (IL) 2007-08-16 WO disclosed
WO-2007016209-A2 PURE 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID SODIUM SALT AND PURIFICATION PROCESS TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-02-08 WO disclosed
WO-2007016208-A2 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID AMMONIUM SALT TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-02-08 WO disclosed
EP-1682522-A1 A PROCESS FOR THE MANUFACTURE OF ZONISAMIDE Wockhardt Limited (IN) 2006-07-26 EP disclosed
WO-2005044808-A1 A PROCESS FOR THE MANUFACTURE OF ZONISAMIDE WOCKHARDT LIMITED (IN) 2005-05-19 WO disclosed