Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308509 | 0.70 | ACHE (0.39) | CHRNA7TSHRACHE | |
| Iodide SCHEMBL1750930 | 0.69 | HTT (0.38) | CHRNA7TSHRACHE | |
| SCHEMBL5291785 | 0.68 | GABRA1 (0.36) | TSHR | |
| SCHEMBL5298975 | 0.68 | LMNA (0.46) | TSHRACHE | |
| SCHEMBL12381060 | 0.68 | GABRA1 (0.34) | TSHR | |
| SCHEMBL22953081 | 0.67 | SLC22A2 (0.38) | — | |
| SCHEMBL1128429 | 0.67 | ACHE (0.42) | ACHE | |
| Bromide SCHEMBL7722238 | 0.65 | BCHE (0.44) | ACHE | |
| Iodide SCHEMBL10722217 | 0.65 | ACHE (0.41) | ACHE | |
| SCHEMBL5302778 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835466-B2 | Synthesis and uses of pyroglutamic acid derivatives | PRODIMED, S.A. (ES) | 2014-09-16 | — | — | US | disclosed |
| US-7671206-B2 | Synthesis and uses of pyroglutamic acid derivatives | PRODIMED, S.A. (ES) | 2010-03-02 | — | — | US | disclosed |
| US-20090163555-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | PRODIMED, S.A. (ES) | 2009-06-25 | — | — | US | disclosed |
| US-20070249678-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | PRODIMED, S.A. (ES) | 2007-10-25 | — | — | US | disclosed |
| WO-2007006418-A1 | IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006131234-A1 | COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249678-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | GLUL, RIMKLA, PHKG1 | CHRNA7 4347/4885CHRNA10 4259/4885CHRNA9 4251/4885 |
| US-20090163555-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | GLUL, RIMKLA, GLS | CHRNA7 4196/4885CHRNA10 4271/4885CHRNA9 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.